Pharmacological targets of SGLT2 inhibition on prostate cancer mediated by circulating metabolites: a drug-target Mendelian randomization study

• Asıl Yazarlar: Yilong Lin (Yazar), Yue Zhang (Yazar), Songsong Wang (Yazar), Lin Cao (Yazar), Ruidan Zhao (Yazar), Xilai Ma (Yazar), Qiaolu Yang (Yazar), Liyi Zhang (Yazar), Qingmo Yang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

BackgroundThe relationship between sodium-glucose cotransporter 2 (SGLT2) inhibitors and prostate cancer is still unknown. Although these inhibitors can influence tumor glycolysis, the underlying mechanism requires further exploration.MethodsA two-sample two-step MR was used to determine 1) causal e...