Low‐intensity low‐frequency ultrasound mediates riboflavin delivery during corneal crosslinking

• Main Authors: Zhe Sun (Author), Zhiming Li (Author), Jin Teng Chung (Author), Laurence Chi Ming Lau (Author), Vishal Jhanji (Author), Ying Chau (Author)
• Format: Book
• Published: Wiley, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We employed the mechanical effect from 40 kHz ultrasound (US) to improve the delivery of riboflavin into corneal stroma for collagen crosslinking, which can benefit the treatment of keratoconus and other corneal ectasias. Experiments were conducted, first with porcine corneas ex vivo and th...