Effect of food on capsule and granule formulations of selumetinib

• 主要な著者: Sarit Cohen‐Rabbie (著者), Alexandra Mattinson (著者), Karen So (著者), Nan Wang (著者), Ronald Goldwater (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2022-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Selumetinib is an oral, potent, and highly selective allosteric MEK1/2 inhibitor approved for the treatment of pediatric patients (aged ≥2 years) with neurofibromatosis type 1 who have symptomatic, inoperable plexiform neurofibromas. A granule formulation of selumetinib is under development...