Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation

• Main Authors: Ramona Vinci (Author), Daniela Pedicino (Author), Alessia D'Aiello (Author), Pellegrino Ciampi (Author), Myriana Ponzo (Author), Alice Bonanni (Author), Giulio Russo (Author), Rocco Antonio Montone (Author), Massimo Massetti (Author), Filippo Crea (Author), Giovanna Liuzzo (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute Coronary Syndromes (ACS) with plaque erosion display dysregulated hyaluronan metabolism, with increased hyaluronidase-2 (HYAL2) expression. However, the expression and the role of this enzyme on platelets has never been explored. We evaluated the platelet's HYAL2 (pltHYAL2) levels on I) s...