Development of a UPLC-MS/MS Method for Pharmacokinetic and Tissue Distribution of Isoeleutherin, Eleutherin, and Eleutherol in Bulbus eleutherinis in Rats

• Main Authors: Peng-Cheng Guo (Author), Jie-Yu Chen (Author), Jing Su (Author), Faisal Raza (Author), Bin Hao (Author), Xin-Yi Wu (Author), Yi-Qing Cheng (Author), Ming-Feng Qiu (Author)
• Format: Book
• Published: Georg Thieme Verlag KG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Bulbus eleutherinis is a classical traditional Dai medicine, and has been widely used in clinical treatment of coronary heart disease (CHD) in Yunnan, China. Naphthoquinone, as the main active compound in Bulbus eleutherinis in treating CHD, mainly contain isoeleutherin, eleutherin, and ele...