Cardiovascular phenotype of the Dmdmdx rat - a suitable animal model for Duchenne muscular dystrophy

• Main Authors: Petra Lujza Szabó (Author), Janine Ebner (Author), Xaver Koenig (Author), Ouafa Hamza (Author), Simon Watzinger (Author), Sandra Trojanek (Author), Dietmar Abraham (Author), Hannes Todt (Author), Helmut Kubista (Author), Klaus Schicker (Author), Séverine Remy (Author), Ignacio Anegon (Author), Attila Kiss (Author), Bruno K. Podesser (Author), Karlheinz Hilber (Author)
• Format: Book
• Published: The Company of Biologists, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Besides skeletal muscle abnormalities, Duchenne muscular dystrophy (DMD) patients present with dilated cardiomyopathy development, which considerably contributes to morbidity and mortality. Because the mechanisms responsible for the cardiac complications in the context of DMD are largely unknown, ev...