S. mansoni SmKI-1 Kunitz-domain: Leucine point mutation at P1 site generates enhanced neutrophil elastase inhibitory activity.
The Schistosoma mansoni SmKI-1 protein is composed of two domains: a Kunitz-type serine protease inhibitor motif (KD) and a C-terminus domain with no similarity outside the genera. Our previous work has demonstrated that KD plays an essential role in neutrophil elastase (NE) binding blockage, in neu...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2021-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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