G6PD deficiency at Sumba in Eastern Indonesia is prevalent, diverse and severe: implications for primaquine therapy against relapsing Vivax malaria.

• Main Authors: Ari Winasti Satyagraha (Author), Arkasha Sadhewa (Author), Vanessa Baramuli (Author), Rosalie Elvira (Author), Chase Ridenour (Author), Iqbal Elyazar (Author), Rintis Noviyanti (Author), Farah Novita Coutrier (Author), Alida Roswita Harahap (Author), J Kevin Baird (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Safe treatment of Plasmodium vivax requires diagnosis of both the infection and status of erythrocytic glucose-6-phosphate dehydrogenase (G6PD) activity because hypnozoitocidal therapy against relapse requires primaquine, which causes a mild to severe acute hemolytic anemia in G6PD deficient patient...