Glucokinase as an emerging anti-diabetes target and recent progress in the development of its agonists

• Main Authors: Yixin Ren (Author), Li Li (Author), Li Wan (Author), Yan Huang (Author), Shuang Cao (Author)
• פורמט: ספר
• יצא לאור: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Type 2 diabetes mellitus is a metabolic disorder with complicated pathogenesis, and mono-target therapy often fails to effectively manage the levels of blood glucose. In recent years, the anti-diabetes target glucokinase (GK) has attracted the attention of researchers. It acts as a glucose sensor, t...