Novel sulindac derivatives: synthesis, characterisation, evaluation of antioxidant, analgesic, anti-inflammatory, ulcerogenic and COX-2 inhibition activity

• Autori principali: Mashooq A. Bhat (Autore), Mohamed A. Al-Omar (Autore), Nawaf A. Alsaif (Autore), Abdulrahman A. Almehizia (Autore), Ahmed M. Naglah (Autore), Suhail Razak (Autore), Azmat Ali Khan (Autore), Naeem Mahmood Ashraf (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

A new series of N'-(substituted phenyl)-2-(1-(4-(methylsulfinyl) benzylidene)−5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide derivatives (1 - 25) were prepared in good yields in an efficient manner. All the compounds were fully characterised by the elemental analysis and spectral data. Synthes...