Novel sulindac derivatives: synthesis, characterisation, evaluation of antioxidant, analgesic, anti-inflammatory, ulcerogenic and COX-2 inhibition activity

• Main Authors: Mashooq A. Bhat (Author), Mohamed A. Al-Omar (Author), Nawaf A. Alsaif (Author), Abdulrahman A. Almehizia (Author), Ahmed M. Naglah (Author), Suhail Razak (Author), Azmat Ali Khan (Author), Naeem Mahmood Ashraf (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new series of N'-(substituted phenyl)-2-(1-(4-(methylsulfinyl) benzylidene)−5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide derivatives (1 - 25) were prepared in good yields in an efficient manner. All the compounds were fully characterised by the elemental analysis and spectral data. Synthes...