Mechanistic Modeling of Maternal Lymphoid and Fetal Plasma Antiretroviral Exposure During the Third Trimester

• Asıl Yazarlar: Babajide Shenkoya (Yazar), Shakir Atoyebi (Yazar), Ibrahim Eniayewu (Yazar), Abdulafeez Akinloye (Yazar), Adeniyi Olagunju (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Pregnancy-induced changes in plasma pharmacokinetics of many antiretrovirals (ARV) are well-established. Current knowledge about the extent of ARV exposure in lymphoid tissues of pregnant women and within the fetal compartment is limited due to their inaccessibility. Subtherapeutic ARV concentration...