In vitro suppression of inflammatory cytokine response by methionine sulfoximine

• Main Authors: Tyler J. Peters (Author), Amruta A. Jambekar (Author), William S. A. Brusilow (Author)
• Formato: Libro
• Publicado: BMC, 2018-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract Background The glutamine synthetase inhibitor methionine sulfoximine (MSO), shown previously to prevent death caused by an inflammatory liver response in mice, was tested on in vitro production of cytokines by mouse peritoneal macrophages triggered with lipopolysaccharide (LPS). Results MSO...