Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins

• প্রধান লেখক: Robin A. Lu (লেখক), Amir A. Zeki (লেখক), Sumati Ram-Mohan (লেখক), Nhan Nguyen (লেখক), Yan Bai (লেখক), Kenneth Chmiel (লেখক), Stevan Pecic (লেখক), Xingbin Ai (লেখক), Ramaswamy Krishnan (লেখক), Chandra C. Ghosh (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Despite maximal use of currently available therapies, a significant number of asthma patients continue to experience severe, and sometimes life-threatening bronchoconstriction. To fill this therapeutic gap, we examined a potential role for the 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR)...