Nerve injury induces robust allodynia and ectopic discharges in Na_v1.3 null mutant mice

• Main Authors: Mallucci Giovanna (Author), Ingram Rachel (Author), Levato Alessandra (Author), Baker Mark D (Author), Nassar Mohammed A (Author), McMahon Stephen B (Author), Wood John N (Author)
• Format: Book
• Published: SAGE Publishing, 2006-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Changes in sodium channel activity and neuronal hyperexcitability contribute to neuropathic pain, a major clinical problem. There is strong evidence that the re-expression of the embryonic voltage-gated sodium channel subunit Na_v1.3 underli...