Neuregulin-1β Partially Improves Cardiac Function in Volume-Overload Heart Failure Through Regulation of Abnormal Calcium Handling

• Asıl Yazarlar: Xuehui Wang (Yazar), Xiaozhen Zhuo (Yazar), Jie Gao (Yazar), Huibing Liu (Yazar), Fei Lin (Yazar), Aiqun Ma (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Neuregulin (NRG-1), an essential stress-mediated paracrine growth factor, has a cardioprotective effect in failing heart. However, the underlying mechanism remains unclear. The role of NRG-1β in heart failure (HF) rats was examined.Methods and Results: Volume-overload HF rat model was cr...