Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells

• 主要な著者: Anke Jaudszus (著者), Stefan Lorkowski (著者), Michael Gruen (著者), Alexander Roth (著者), Gerhard Jahreis (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2014-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Synthetic antagonists of the nuclear receptor PPARγ such as GW9662 are widely used to elucidate receptor-mediated ligand effects. In addition and complementary to recent work, we examined whether GW9662 is suitable to serve for mechanistic investigation in T-helper cells. Human peripheral blood mono...