Effect of Dornase Alfa on the Lung Clearance Index in Children with Cystic Fibrosis: A Lesson from a Case Series

• मुख्य लेखकों: Vito Terlizzi (लेखक), Giuseppe Fabio Parisi (लेखक), Beatrice Ferrari (लेखक), Chiara Castellani (लेखक), Sara Manti (लेखक), Salvatore Leonardi (लेखक), Giovanni Taccetti (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Dornase alfa (DNase) is the only mucus-degrading agent that has proven efficacy in cystic fibrosis (CF). Few studies have evaluated the effects of DNase on the lung clearance index (LCI). We report the experience of two CF centers in which LCI monitoring was used to evaluate the efficacy...