The Relationship between Pulmonary Damage and Peripheral Vascular Manifestations in Systemic Sclerosis Patients

• Main Authors: Barbara Ruaro (Author), Marco Confalonieri (Author), Francesco Salton (Author), Barbara Wade (Author), Elisa Baratella (Author), Pietro Geri (Author), Paola Confalonieri (Author), Metka Kodric (Author), Marco Biolo (Author), Cosimo Bruni (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Systemic sclerosis (SSc) is an autoimmune disease, characterized by the presence of generalized vasculopathy and tissue fibrosis. Collagen vascular disorder in SSc is due to fibroblast and endothelial cell dysfunctions. This leads to collagen overproduction, vascular impairment and immune system abn...