Nicotine regulates autophagy of human periodontal ligament cells through α7 nAchR that promotes secretion of inflammatory factors IL-1β and IL-8

• Main Authors: Yang Du (Author), Kuan Yang (Author), Zhifei Zhou (Author), Lizheng Wu (Author), Lulu Wang (Author), Yujiang Chen (Author), Xin Ge (Author), Xiaojing Wang (Author)
• Format: Book
• Published: BMC, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Nicotine is an important risk factor and the main toxic component associated with periodontitis. However, the mechanism of nicotine induced periodontitis is not clear. To investigated the mechanism through which nicotine regulates autophagy of human periodontal ligament cells (hP...