HO-3867 Induces Apoptosis via the JNK Signaling Pathway in Human Osteosarcoma Cells

• Main Authors: Peace Wun-Ang Lu (Author), Chia-Hsuan Chou (Author), Jia-Sin Yang (Author), Yi-Hsien Hsieh (Author), Meng-Ying Tsai (Author), Ko-Hsiu Lu (Author), Shun-Fa Yang (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metastatic osteosarcoma often results in poor prognosis despite the application of surgical en bloc excision along with chemotherapy. HO-3867 is a curcumin analog that induces cell apoptosis in several cancers, but the apoptotic effect and its mechanisms on osteosarcoma cells are still unknown. Afte...