Systematic expression analysis of genes related to generation of action potentials in human iPS cell-derived cardiomyocytes

• Autors principals: Masami Kodama (Autor), Kazuharu Furutani (Autor), Reiko Kimura (Autor), Tomoko Ando (Autor), Kazuho Sakamoto (Autor), Shushi Nagamori (Autor), Takashi Ashihara (Autor), Yoshihisa Kurachi (Autor), Yuko Sekino (Autor), Tetsushi Furukawa (Autor), Yasunari Kanda (Autor), Junko Kurokawa (Autor)
• Format: Llibre
• Publicat: Elsevier, 2019-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a valuable tool to characterize the pharmacology and toxic effects of drugs on heart cells. In particular, hiPSC-CMs can be used to identify drugs that generate arrhythmias. However, it is unclear whether the expression of ge...