Valproic acid induced acute liver injury resulting in hepatic encephalopathy- a case report and literature review

• Main Authors: Vijay Gayam (Author), Amrendra Kumar Mandal (Author), Mazin Khalid (Author), Binav Shrestha (Author), Pavani Garlapati (Author), Mowyad Khalid (Author)
• Format: Book
• Published: Greater Baltimore Medical Center, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Valproic acid (VPA) is a commonly used agent in the management of seizures and psychiatric disorders. Hyperammonemia is a common complication of VPA with 27.8% of patients having elevated levels - that is unrelated to hepatotoxicity and normal transaminases. Common side effects include obesity, insu...