Toxicology and Pharmacokinetics Study of Intradiscal Injection of Simvastatin in Rabbits

• Main Authors: Xiaodong Huang (Author), Wei He (Author), Weiheng Wang (Author), Quanchun Fan (Author), Xiaojian Ye (Author), Zenghui Wu (Author), Chia-Ying Lin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To test the pharmacokinetics and toxicology of whole organs and tissues after intradiscal injection of simvastatin in rabbits. To provide the information needed to support human clinical trials. Twelve male and twelve female rabbits were randomly divided into four groups: control group (0 mg/ml), lo...