Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis

• Prif Awduron: Xiaoli Li (Awdur), Qianqian Li (Awdur), Bin Xiong (Awdur), Huiling Chen (Awdur), Xiaochun Wang (Awdur), Dekui Zhang (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2022-09-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Background and aims: Discoidin domain receptor 1 (DDR1) encodes a receptor tyrosine kinase involved in multiple physiological and pathological processes. DDR1 is expressed in the intestinal epithelium, but its role in Ulcerative Colitis (UC) is poorly understand. This study aimed to identify the fun...