Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of the QX002N anti-IL-17 Monoclonal Antibody: A Phase I, Randomized, Double-Blind, Single Ascending Dose Study in Healthy Chinese Volunteers

Background: The innovative injection of interleukin 17 A (IL-17A) monoclonal antibody QX002N is being developed to treat active ankylosing spondylitis and plaque psoriasis in adults.Objective: This study investigated the pharmacokinetics (PKs), pharmacodynamics (PDs) safety, tolerability, and immuno...

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Main Authors: Min Wu (Author), Hong Zhang (Author), Qianqian Li (Author), Hong Chen (Author), Min Fang (Author), Lizhi Yang (Author), Yanhua Ding (Author)
Format: Book
Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
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