Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling

• Main Authors: Yeong Chan Ryu (Author), You-Rin Kim (Author), Jiyeon Park (Author), Sehee Choi (Author), Won-Ji Ryu (Author), Geon-Uk Kim (Author), Eunhwan Kim (Author), Yumi Hwang (Author), Heejene Kim (Author), Gyoonhee Han (Author), Soung-Hoon Lee (Author), Kang-Yell Choi (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hair follicle stem cells (HFSCs) utilize glycolytic metabolism during their activation and anagen induction. However, the role of pyruvate kinase M2 (PKM2), which catalyzes the final step of glycolysis, in hair regeneration has not been elucidated. In this study, we investigated the expression patte...