Tilidine and dipyrone (metamizole) in cold pressor pain: A pooled analysis of efficacy, tolerability, and safety in healthy volunteers

• Egile Nagusiak: Julian Kleine‐Borgmann (Egilea), Johannes Wilhelmi (Egilea), Johannes Kratel (Egilea), Frederik Baumann (Egilea), Katharina Schmidt (Egilea), Matthias Zunhammer (Egilea), Ulrike Bingel (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2021-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract The cold pressor test (CPT) is widely implemented and offers a simple, experimental acute pain model utilizing cold pain. Previous trials have frequently paired the CPT with opioids in order to investigate the mechanisms underlying pharmacological analgesia, due to their known analgesic eff...