High throughput virtual screening and validation of Plant-Based EGFR L858R kinase inhibitors against Non-Small cell lung Cancer: An integrated approach Utilizing GC-MS, network Pharmacology, Docking, and molecular dynamics

• Auteurs principaux: Kun Gao (Auteur), Zujian Chen (Auteur), Na Zhang (Auteur), Pu Jiang (Auteur)
• Format: Livre
• Publié: Elsevier, 2024-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Lung cancer ranks as the 2nd most common cancer globally. It's the most prevalent cancer in men and the 2nd most common in women. The prominent events in EGFR-mutated non-small-cell lung cancer (NSCLC) include the emergence of the L858R mutation within EGFR exon 21. Despite the promising effica...