Degradation of MK2 with natural compound andrographolide: A new modality for anti-inflammatory therapy

• मुख्य लेखकों: Quy T.N. Tran (लेखक), Phyllis X.L. Gan (लेखक), Wupeng Liao (लेखक), Yu Keung Mok (लेखक), Christina L.L. Chai (लेखक), W.S. Fred Wong (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The p38MAPK-MK2 signaling axis functions as an initiator of inflammation. Targeting the p38MAPK-MK2 signaling axis represents a direct therapeutic intervention of inflammatory diseases. We described here a novel role of andrographolide (AG), a small-molecule ent-labdane natural compound, as an inhib...