BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss

• Main Authors: Chenhui Cai (Author), Wenhui Hu (Author), Ying Zhang (Author), Xu Hu (Author), Sizhen Yang (Author), Hao Qiu (Author), Rujie Wang (Author), Min Ma (Author), Yiyun Qiu (Author), Tongwei Chu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoporosis is a common aging-related metabolic disease that mainly occurs in older adults and postmenopausal women. Despite advances in anti-osteoporosis treatment, outcomes remain unsatisfactory due to detrimental side effects. BCI hydrochloride (BCI), a selective dual-specificity phosphatase 6 (...