Novel Aminoguanidine Hydrazone Analogues: From Potential Antimicrobial Agents to Potent Cholinesterase Inhibitors

• Main Authors: Martin Krátký (Author), Šárka Štěpánková (Author), Klára Konečná (Author), Katarína Svrčková (Author), Jana Maixnerová (Author), Markéta Švarcová (Author), Ondřej Janďourek (Author), František Trejtnar (Author), Jarmila Vinšová (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of thirty-one hydrazones of aminoguanidine, nitroaminoguanidine, 1,3-diaminoguanidine, and (thio)semicarbazide were prepared from various aldehydes, mainly chlorobenzaldehydes, halogenated salicylaldehydes, 5-nitrofurfural, and isatin (yields of 50-99%). They were characterized by spectral...