Reduction-responsive PEtOz-SS-PCL micelle with tailored size to overcome blood-brain barrier and enhance doxorubicin antiglioma effect

• Main Authors: Yuling Li (Author), Li Baiyang (Author), Bu Leran (Author), Wang Zhen (Author), Xie Yandong (Author), Du Baixiang (Author), Zhu Dandan (Author), Zhu Yufu (Author), Liang Jun (Author), Yu Rutong (Author), Liu Hongmei (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of novel reduction-responsive micelles with tailored size were designed and prepared to release doxorubicin (DOX) for treating glioma, which were developed based on amphiphilic block copolymer poly (2-ethyl-2-oxazoline)-b-poly (ε-caprolactone) (PEtOz-SS-PCL) and the micelle size could be re...