The interaction between autophagy and the epithelial-mesenchymal transition mediated by NICD/ULK1 is involved in the formation of diabetic cataracts

• Main Authors: Jiyuan Ma (Author), Wei Ye (Author), Yunshu Yang (Author), Tong Wu (Author), Yafen Wang (Author), Ji Li (Author), Rui Pei (Author), Mengmei He (Author), Luning Zhang (Author), Jian Zhou (Author)
• Format: Book
• Published: BMC, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cataracts are the leading cause of blindness and a common ocular complication of diabetes. The epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) and altered autophagic activity occur during the development of diabetic cataracts. The disturbed interaction of...