In vivo antimalarial effect of 1-hydroxy-5,6,7-trimethoxyxanthone isolated from Mammea siamensis T. Anders. flowers: pharmacokinetic and acute toxicity studies

• Hauptverfasser: Prapaporn Chaniad (Verfasst von), Arnon Chukaew (Verfasst von), Prasit Na-ek (Verfasst von), Gorawit Yusakul (Verfasst von), Litavadee Chuaboon (Verfasst von), Arisara Phuwajaroanpong (Verfasst von), Walaiporn Plirat (Verfasst von), Atthaphon Konyanee (Verfasst von), Abdi Wira Septama (Verfasst von), Chuchard Punsawad (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2024-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background The potent antiplasmodial activity of 1-hydroxy-5,6,7-trimethoxyxanthone (HTX), isolated from Mammea siamensis T. Anders. flowers, has previously been demonstrated in vitro. However, its in vivo activity has not been reported. Therefore, this study aimed to investigate the antima...