Pretreatment with 3-methyladenine ameliorated Pseudomonas aeruginosa-induced acute pneumonia by inhibiting cell death of neutrophils in a mouse infection model

• Main Authors: Lei Yue (Author), Han Cao (Author), Jialong Qi (Author), Jin Yuan (Author), Xin Wang (Author), Yunfei Wang (Author), Bin Shan (Author), Huaxin Ke (Author), Hua Li (Author), Ning Luan (Author), Cunbao Liu (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pseudomonas aeruginosa is one of the leading causes of nosocomial infections worldwide. Clinical isolates that are resistant to multiple antimicrobials make it intractable. The interactions between P. aeruginosa and host cell death have multiple effects on bacterial clearance and inflammation; howev...