Trichinella spiralis cathepsin L damages the tight junctions of intestinal epithelial cells and mediates larval invasion.

• Main Authors: Ruo Dan Liu (Author), Xiang Yu Meng (Author), Chen Le Li (Author), Xin Zhi Lin (Author), Qiu Yi Xu (Author), Han Xu (Author), Shao Rong Long (Author), Jing Cui (Author), Zhong Quan Wang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Cathepsin L, a lysosomal enzyme, participates in diverse physiological processes. Recombinant Trichinella spiralis cathepsin L domains (rTsCatL2) exhibited natural cysteine protease activity and hydrolyzed host immunoglobulin and extracellular matrix proteins in vitro,...