Phytochemicals That Interfere With Drug Metabolism and Transport, Modifying Plasma Concentration in Humans and Animals

• Main Authors: Josefina Gómez-Garduño (Author), Renato León-Rodríguez (Author), Radamés Alemón-Medina (Author), Beatriz E. Pérez-Guillé (Author), Rosa E. Soriano-Rosales (Author), Ailema González-Ortiz (Author), Juan L. Chávez-Pacheco (Author), Edelmira Solorio-López (Author), Paola Fernandez-Pérez (Author), Liliana Rivera-Espinosa (Author)
• Format: Book
• Published: SAGE Publishing, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phytochemicals (Pch) present in fruits, vegetables and other foods, are known to inhibit or induce drug metabolism and transport. An exhaustive search was performed in five databases covering from 2000 to 2021. Twenty-one compounds from plants were found to modulate CYP3A and/or P-gp activities and...