Il12a Deletion Aggravates Sepsis-Induced Cardiac Dysfunction by Regulating Macrophage Polarization

• Main Authors: Zhen Wang (Author), Menglin Liu (Author), Di Ye (Author), Jing Ye (Author), Menglong Wang (Author), Jianfang Liu (Author), Yao Xu (Author), Jishou Zhang (Author), Mengmeng Zhao (Author), Yongqi Feng (Author), Shuwan Xu (Author), Wei Pan (Author), Zhen Luo (Author), Dan Li (Author), Jun Wan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiac dysfunction is a well-recognized complication of sepsis and is associated with the outcome and prognosis of septic patients. Evidence suggests that Il12a participates in the regulation of various cardiovascular diseases, including heart failure, hypertension and acute myocardial infarction....