Nuclear factor erythroid 2 - related factor 2 and its relationship with cellular response in nickel exposure: a systems biology analysis

• Main Authors: Luisa Jiménez-Vidal (Author), Pedro Espitia-Pérez (Author), José Torres-Ávila (Author), Dina Ricardo-Caldera (Author), Shirley Salcedo-Arteaga (Author), Claudia Galeano-Páez (Author), Karina Pastor-Sierra (Author), Lyda Espitia-Pérez (Author)
• Format: Book
• Published: BMC, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Nickel and nickel-containing compounds (NCC) are known human carcinogens. However, the precise molecular mechanisms of nickel-induced malignant transformation remain unknown. Proposed mechanisms suggest that nickel and NCC may participate in the dual activation/inactivation of en...