Role of Cytosolic Serine Hydroxymethyl Transferase 1 (SHMT1) in Phosphate-Induced Vascular Smooth Muscle Cell Calcification

• Hoofdauteurs: Beate Boehme (Auteur), Nadeshda Schelski (Auteur), Manousos Makridakis (Auteur), Laura Henze (Auteur), Antonia Vlahou (Auteur), Florian Lang (Auteur), Burkert Pieske (Auteur), Ioana Alesutan (Auteur), Jakob Voelkl (Auteur)
• Formaat: Boek
• Gepubliceerd in: Karger Publishers, 2018-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background/Aims: Hyperphosphatemia promotes medial vascular calcification, at least partly, by induction of osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). The complex signaling pathways regulating this process are still incompletely understood. The present study in...