Poly(HydroxyButyrate-co-HydroxyValerate) (PHBHV) Nanocarriers for Silymarin Release as Adjuvant Therapy in Colo-rectal Cancer

• Главные авторы: Ionut-Cristian Radu (Автор), Ariana Hudita (Автор), Catalin Zaharia (Автор), Paul O. Stanescu (Автор), Eugenia Vasile (Автор), Horia Iovu (Автор), Miriana Stan (Автор), Octav Ginghina (Автор), Bianca Galateanu (Автор), Marieta Costache (Автор), Peter Langguth (Автор), Aristidis Tsatsakis (Автор), Kelly Velonia (Автор), Carolina Negrei (Автор)
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• Опубликовано: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Предметы: article
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The aim of this study was to address one of the major challenges of the actual era of nanomedicine namely, the bioavailability of poorly water soluble drugs such as Silymarin. We developed new, biodegradable, and biocompatible nanosized shuttles for Silymarin targeted delivery in colon-cancer cells....