The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme

The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme

The membrane-bound human carbonic anhydrase (hCA) IX is widely recognized as a marker of tumor hypoxia and a prognostic factor within several human cancers. Being undetected in most normal tissues, hCA-IX implies the pharmacotherapeutic advent of reduced off-target adverse effects. We assessed the p...

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Main Authors: Azizah M. Malebari (Author), Tarek S. Ibrahim (Author), Ibrahim M. Salem (Author), Ismail Salama (Author), Ahdab N. Khayyat (Author), Samia M. Mostafa (Author), Osama I. El-Sabbagh (Author), Khaled M. Darwish (Author)
Format: Book
Published: MDPI AG, 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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