Surface Functionalization of Silica Nanoparticles: Strategies to Optimize the Immune-Activating Profile of Carrier Platforms

• Main Authors: Benjamin Punz (Author), Litty Johnson (Author), Mark Geppert (Author), Hieu-Hoa Dang (Author), Jutta Horejs-Hoeck (Author), Albert Duschl (Author), Martin Himly (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Silica nanoparticles (SiNPs) are generally regarded as safe and may represent an attractive carrier platform for nanomedical applications when loaded with biopharmaceuticals. Surface functionalization by different chemistries may help to optimize protein loading and may further impact uptake into th...