Exosome-Derived ADAM17 Promotes Liver Metastasis in Colorectal Cancer

• Main Authors: Jinbing Sun (Author), Zhihua Lu (Author), Wei Fu (Author), Kuangyi Lu (Author), Xiuwen Gu (Author), Feng Xu (Author), Jiamin Dai (Author), Yang Yang (Author), Jianlong Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exosomes derived from cancer cells are deemed important drivers of pre-metastatic niche formation at distant organs, but the underlying mechanisms of their effects remain largely unknow. Although the role of ADAM17 in cancer cells has been well studied, the secreted ADAM17 effects transported via ex...