A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development

• Prif Awduron: Trevor N. Johnson (Awdur), Ben G. Small (Awdur), Eva Gil Berglund (Awdur), Karen Rowland Yeo (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Wiley, 2021-09-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Pediatric physiologically‐based pharmacokinetic (PBPK) models have broad application in the drug development process and are being used not only to project doses for clinical trials but increasingly to replace clinical studies. However, the approach has yet to become fully integrated in regulatory s...