Inhibition of epigenetic reader proteins by apabetalone counters inflammation in activated innate immune cells from Fabry disease patients receiving enzyme replacement therapy

Inhibition of epigenetic reader proteins by apabetalone counters inflammation in activated innate immune cells from Fabry disease patients receiving enzyme replacement therapy

Abstract Fabry disease (FD) is a rare X‐linked disorder of lipid metabolism, characterized by the accumulation of globotriaosylceramide (Gb3) due to defective the lysosomal enzyme, α‐galactosidase. Gb3 deposits activate immune‐mediated systemic inflammation, ultimately leading to life‐threatening co...

Full description

Saved in:
Bibliographic Details
Main Authors: Li Fu (Author), Sylwia Wasiak (Author), Laura M. Tsujikawa (Author), Brooke D. Rakai (Author), Stephanie C. Stotz (Author), Norman C. W. Wong (Author), Jan O. Johansson (Author), Michael Sweeney (Author), Connie M. Mohan (Author), Aneal Khan (Author), Ewelina Kulikowski (Author)
Format: Book
Published: Wiley, 2022-06-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items