Procaine, a State-Dependent Blocker, Inhibits HERG Channels by Helix Residue Y652 and F656 in the S6 Transmembrane Domain
The article evaluated the inhibitory action of procaine on wild-type and mutated HERG potassium channel current (IHERG) to determine whether mutations in the S6 region are important for the inhibition of IHERG by procaine. HERG channels (WT, Y652A, and F656A) were expressed in Xenopus laevis oocytes...
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Format: | Book |
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Elsevier,
2013-01-01T00:00:00Z.
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A1234.567 |
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