Myeloid cells as potential targets for immunotherapy in pediatric gliomas

• Main Authors: Stephen C. Frederico (Author), Nikhil Sharma (Author), Corbin Darling (Author), Suchet Taori (Author), Alexandra C. Dubinsky (Author), Xiaoran Zhang (Author), Itay Raphael (Author), Gary Kohanbash (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pediatric high-grade glioma (pHGG) including pediatric glioblastoma (pGBM) are highly aggressive pediatric central nervous system (CNS) malignancies. pGBM comprises approximately 3% of all pediatric CNS malignancies and has a 5-year survival rate of approximately 20%. Surgical resection and chemorad...