Identification of a novel P2X7 antagonist using structure-based virtual screening

P2X4 and P2X7 receptors are ATP-gated ion channels, which play important roles in neuropathic and inflammatory pain, and as such they are important drug targets in diseases of inflammatory origin. While several compounds targeting P2X4 and P2X7 receptors have been developed using traditional high-th...

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Main Authors: Gaia Pasqualetto (Author), Marika Zuanon (Author), Andrea Brancale (Author), Mark T. Young (Author)
Format: Book
Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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