Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease

• Main Authors: Ping Bai (Author), Prasenjit Mondal (Author), Frederick A. Bagdasarian (Author), Nisha Rani (Author), Yan Liu (Author), Ashley Gomm (Author), Darcy R. Tocci (Author), Se Hoon Choi (Author), Hsiao-Ying Wey (Author), Rudolph E. Tanzi (Author), Can Zhang (Author), Changning Wang (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although the epigenetic regulatory protein histone deacetylase 6 (HDAC6) has been recently implicated in the etiology of Alzheimer's disease (AD), little is known about the role of HDAC6 in the etiopathogenesis of AD and whether HDAC6 can be a potential therapeutic target for AD. Here, we perfo...